SLCO1C1 (solute carrier organic anion transporter family, member 1C1)
Other Symbols:
OATP-F, OATP1, OATP1C1, OATPRP5, SLC21A14
Disease relevance:
This gene belongs to the organic anion transporter family. It is a thyroid hormone transporter found at the blood-brain barrier. Polymorphisms in the gene, especially OATP1C1-intron3C > T and the OATP1C1-C3035T, are related to [...]
SLC6A4 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 4)
Other Symbols:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, hSERT
1) Disease relevance:
This gene belongs to the sodium:neurotransmitter symporter family and is incharge of transporting the neurotransmitter serotonin from synaptic spaces to presynaptic neurons. It is an important regulator of the serotonergic neurotransmission. [...]
SLC6A3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3)
Other Symbols:
DAT, DAT1
1) Disease relevance:
This gene is a dopamine transporter. It belongs to the sodium- and chloride-dependent neurotransmitter transporter family. Variations in the gene are linked to idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, and susceptibility to Parkinson [...]