The Role of Efflux Transporter Proteins in Nonalcoholic Fatty Liver Diseases (NAFLDs)

Efflux transporter proteins are in charge of the excretion of numerous xenobiotics and endobiotics. They are important for normal liver and kidney functions. Nonalcoholic fatty liver diseases (NAFLDs) are usually shown as a range of ailments including simple fatty liver (SFL) and nonalcoholic steatohepatitis (NASH). Exploring the role of efflux transporter proteins in nonalcoholic fatty liver [...]

The Membrane Transporter Protein, Hepatic Fatty Acid Transport Protein 5, and Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease is often associated with obesity and type 2 diabetes. The disease can often be caused by a high fat diet. The inhibition of hepatic fatty acid uptake may have therapeutic potentials. It would be interesting to find out the genetic basis of such process.

Recently researchers in California studied the relationship between [...]

The Potential of Chinese Herbal Extracts for Parkinson’s Disease Treatment: The Regulation Effects on the Dopamine Transporter (DAT)

Chinese herbal medicine has been found helpful for relieving neurological diseases. For example, common flowering quince (FQ) extract has been applied to the treatment of diseases including neuralgia, migraine, and depression. The herb is from the fruit of Chaenomeles speciosa (Sweet) Nakai.

However, the mechanisms of these herbs are still unknown. Researchers in China recently evaluated the [...]