Anxiety and Polymorphisms in the Serotonin Transporter

    September 19, 2014
    Psychoneuroimmunology

    Anxiety has been associated with transporter-assisted uptake of serotonin.  Many antidepressant and antianxiety drugs are selective serotonin reuptake inhibitors (SSRIs). Polymorphisms of the gene for the serotonin transporter (SERT, or SLC6A4) have been found to influence its functions and activities. For example, 5-HTTLPR may decrease the transcriptional productivity of the gene’s promoter, leading to lower expression of serotonin transporters and lower uptake rates of serotonin in lymphoblasts (Lesch et al., …Read the Rest

    Genetic Factors, Quantitative Trait Loci, and Human Personality

    September 4, 2014
    Psychoneuroimmunology

    Both genetic and environmental factors can influence human personality. Genetic factors may affect about half of trait disparity. Their effects …Read the Rest

    Aging, Social Support, and Leukocyte Telomere Length (LTL)

    August 5, 2014
    Psychoneuroimmunology

    Aging and psychological conditions may influence the leukocyte telomere length (LTL) (Carroll et al., 2013; Müezzinler et al., 2013). A …Read the Rest

    Rheumatoid Arthritis, Fibromyalgia Syndrome, and Sleep Quality

    August 1, 2014
    Psychoneuroimmunology

    Patients with rheumatoid arthritis (RA) and fibromyalgia syndrome (FMS) often have poor sleep quality (Ulus et al., 2012; Nicassio et …Read the Rest

    Depression, Anxiety, and Abnormal Diurnal Cortisol Patterns

    July 26, 2014
    Psychoneuroimmunology

    The functional alterations of the hypothalamic-pituitary-adrenal (HPA) axis have been related to not only major depression disorder (MDD) and anxiety …Read the Rest

    Stress, Depression, and Inflammation

    July 9, 2014
    Psychoneuroimmunology

    Inflammation is a risk factor for many aging problems such as metabolic syndrome, Type 2 diabetes, cardiovascular disease, and frailty …Read the Rest

    Depression, Antidepressant Treatment, and Herpes Zoster Vaccine

    July 1, 2014
    Psychoneuroimmunology

    Depression and other psychological problems may influence the effects of vaccines, as studies in psychoneuroimmunology have shown. For example, the …Read the Rest

    Psychoneuroimmunology, Stress Responses, and Chronic Inflammation

    June 18, 2014
    Psychoneuroimmunology

    The interactions between the nervous and immune systems have been associated with psychosocial stress, peripheral inflammation, and chronic diseases (Liezmann …Read the Rest

    PPARs, Psychoneuroimmunology, and Potential Treatment of Psychiatric Disorders

    June 12, 2014
    Psychoneuroimmunology

    Peroxisome Proliferator-Activated Receptors (PPARs) are a group of transcription factors that play important roles in glucose homeostasis, fatty acid and …Read the Rest

    The C-reactive Protein, Socioeconomic Status, Stress, and Inflammation

    June 10, 2014
    Psychoneuroimmunology

    Psychological stress has been associated with elevated inflammation and the risks of many physical illnesses such as heart disease. However, …Read the Rest

    Psychoneuroimmunology and Addictive Disorders: Potential New Therapies

    June 6, 2014
    Psychoneuroimmunology

    Addictive disorders are often chronic relapsing problems with high health, social, and economic costs. Problems such as alcohol use disorders …Read the Rest

    Post-Traumatic Stress Disorder (PTSD), Stress Responses, and Personalized Care

    June 5, 2014
    Psychoneuroimmunology

    The symptoms of trauma-related disorders include both psychological and physiological signs. Evolutionary perspectives of trauma-related disorders have related the primitive …Read the Rest

    Psychoneuroimmunology of Schizophrenia and Anti-Inflammatory Drugs

    May 30, 2014
    Psychoneuroimmunology

    Studies in the psychoneuroimmunology of schizophrenia have revealed not only the neurological and cognitive alterations, but also the continuous systemic …Read the Rest

    The Associations between Depression and Chronic Diseases

    May 22, 2014
    Psychoneuroimmunology

    Depression is becoming a leading cause of disability with loss of work days globally. It is also one of the …Read the Rest

    Childhood Abuse and Higher Health Risks across Multiple Systems in Adulthood

    April 23, 2014
    Psychoneuroimmunology

    Although childhood abuse occur in the early stages of life, the powerful adverse influences on health extend to the adulthood …Read the Rest

    Behavioral Problems in Cancer Patients and Survivors: Factors in Psychoneuroimmunology

    April 4, 2014
    Psychoneuroimmunology

    Behavioral symptoms are commonly seen in cancer patients and survivors. For example, in breast cancer patients, such symptoms include depression, …Read the Rest

    Effects of Psychosocial Therapies for Cancer Patients: Psychoneuroimmunology (PNI)-Based Analysis

    March 28, 2014
    Psychoneuroimmunology

    Cancer patients often have psychological problems too, such as stress and depression. It is critical to address the psychosocial demands …Read the Rest

    Music, Stress and Anxiety Relief, and Psychoneuroimmunology

    March 25, 2014
    Psychoneuroimmunology

    Music is very beneficial for health, especially in the aspect of psychoneuroimmunology (PNI). Music has been found to have effects …Read the Rest

    Childhood Trauma, Life Stress, and Risk Factors for Chronic Fatigue

    March 18, 2014
    Psychoneuroimmunology

    Chronic fatigue syndrome (CFS) is a common health problem, especially in cancer survivors. To provide better care and prevention for …Read the Rest

    Grief, Bereavement and Immune Dysfunction: The Role of Psychoneuroimmunology

    March 10, 2014
    Psychoneuroimmunology

    Mental and emotional reactions such as grief and bereavement have been linked to cortisol responses and neuroendocrine activations, as well …Read the Rest

    Autism Spectrum Disorders (ASD), Cytokines, and Immune Functions

    March 5, 2014
    Psychoneuroimmunology

    Autism spectrum disorders (ASD) has been associated with the malfunctions of multiple biological systems and pathways, especially the cytokines of …Read the Rest

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